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Japanese-B Viral Encephalitis with a Biphasic Illness Pattern and Recovery after Intravenous Immunoglobulin Therapy

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À̺´Âù(Lee Byung-Chan) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ½Å°æ°úÇб³½Ç
ÀüÁö¿¹(Jeon Ji-Ye) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ½Å°æ°úÇб³½Ç
¹®ÇýÁø(Moon Hye-Jin) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ½Å°æ°úÇб³½Ç
ÀÓÁ¤±Ù(Lim Jeong-Geun) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ½Å°æ°úÇб³½Ç
Á¶¿ë¿ø(Cho Yong-Won) - °è¸í´ëÇб³ ÀÇ°ú´ëÇÐ ½Å°æ°úÇб³½Ç

Abstract

Japanese-B viral encephalitis (JE) usually has a monophasic illness pattern. A 45-year-old woman in an altered mentality had improved over 1 month. About 1 week after the initial improvement, the patient became comatose with aggravated EEG and MRI findings. Assays of cerebrospinal fluid and serum were positive for the IgM antibody to Japanese-B virus. After intravenous immunoglobulin (IVIG) infusion, the patient recovered. We report a patient with JE who showed a biphasic illness pattern and recovered after IVIG therapy.

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Japanese-B viral encephalitis, IVIG, Biphasic illne
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DOI
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ICD 03
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